| Epistemology | Emphasis on investigation, evidence, causality | 1st vs 3rd person methods; validity of introspection; differing goals (liberation vs. description) |
| Interdependence | Dependent origination & systems theory, ecology, quantum physics | Different metaphysical assumptions; soteriological vs. descriptive aims; superficial analogy risk |
| Consciousness | Shared interest; collaboration potential (neuroscience) | Materialism vs. non-reductionism/primacy of mind; 1st/3rd person gap; 'Hard Problem' |
| Rebirth | (Minimal convergence) | Incompatibility with physicalism; lack of evidence; philosophical critiques |
| Karma | (Limited: psychological conditioning?) | Lack of evidence (trans-lifetime); scientific vs. moral causality; performative function |
| Self (Anattā) | Apparent resonance with 'constructed self' in neuroscience | Conflation (soteriological vs. descriptive); functional role of self; therapeutic risks |
| Aims/values | Shared interest in well- being (surface) | Liberation/ethics vs. description/control; science & power vs. non-harming/detachment |